Centre for Bioinformatics  

In view of rapidly growing importance of Information Technology in Biotechnology teaching and research, related software, data management, communication etc., Centre for Bioinformatics (a sub-DIC under BTIS programme) was sanctioned by Department of Biotechnology, Govt. of India in November, 1998. Over the last twelve years, this centre has acquired many databases and softwares and has round the clock Internet connectivity.  

The Centre has 3 servers, 42 PCs, 1 scanner, 13 printers, 1 LCD projector, 2 IBM  &  2 HP Laptops , 4 Web Camera, 2 Digital Camera, 3 External CD/DVD Writers, 2 Photocopier machines, several software and databases. All computers are connected   to Internet through 512 KBPS lease line from BSNL under campus networking.

• It is extensively used by PG students in Biotechnology, Bioscience and Bioinformatics, Ph.D. students and the teaching faculty in the following ways:

•    Searching literature/databases of their own research interest.

•    E-mail facility                               

•    Computational work.    

• The services of the Centre for Bioinformatics include analysis of   biological data, bibliographic references to published literature in Science and Technology.
   

Designation

Ms. Saroj Yadav

Information Officer

Mrs. Kiran Shanti

Technical Assistant

Mr. S. R. Choudhary

Computer Operator

Mr. Amit Goyal

Data Entry Operator  

The Ph.D. students carry out research in various disciplines of Biotechnology, Bioscience and Bioinformatics.  There are sponsored research projects with teaching faculty of the department. Some of the Agricultural Biotechnology related research topics are: Phytoalexins; Immobilization of enzymes; Fluoride toxicity; Reclamation of desert soils using plants; Tissue culture of arid zone species etc.    

A  research collaboration in the area of Crop Biotechnology (on stress adaptation of plants of local region) was carried out between Prof. Vinay Sharma’s laboratory at this Department and Prof. U. Luettge’s laboratory at Institute of Botany, Technical University, Darmstadt. From this department, on invitation of DAAD, Prof. Vinay Sharma visited Germany (May- June, 2000 for 2 months) and then thrice later in 2001, 2002 and 2003 under DST-DAAD project. Dr. Nilima Kumari, Sr. Lecturer visited Germany in 2001, 2002 and 2003 for 3 months each under DST-DAAD project.

Prof. Vinay Sharma has been a Visiting Professor at the Department of Molecular Biology and Microbiology, University of Florida, USA (January to June, 2006).

Dr. Bhumi Nath Tripathi, Senior Lecturer was awarded the prestigious DBT Young Scientist Overseas Associateship and visited University of Bielefeld, Germany (July to November, 2006). 

Dr. Bhumi Nath Tripathi, Senior Lecturer was a Visiting Scientist at the Research Institute of Bioresources, Okayama University, Japan (October 2007-March 2008).  

Prof. Vinay Sharma has been a Visiting Professor at the Research Institute of Bioresources, Okayama University, Japan (August, 2008).

Dr. Nilima Kumari, Associate Professor was a Visiting Scientist at the Department of Biology, University of Turku, Finland for a few months beginning February, 2010.

Prof. Vinay Sharma has been a Visiting Professor at the Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Germany (May to June, 2010).

Prof. Vinay Sharma has been a Visiting Professor at the Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Germany (October to November, 2010).

• Some of the important databases in Biological Sciences that are currently available are: Medline Standard, Agris, Agricola, Chrome Circle Application, Biotechnology Abstracts and Indian Forester Information System.
   

• To cater to the regional and national needs, the Centre has also developed database on "Biotechnological Industries of Rajasthan", “SSR Database of Citrus sinensis,”, “Database for Simple Sequence Repeats of Takifugu rubripus”, “Database of Diterpene Synthase Gene”and "Flora of Indian Desert". “Database of Plant Host-Pathogen Interaction” is in progress.

Biotechnological Industries of Rajasthan

Bioinformatics /Biotechnology

SSR Database of Citrus sinensis

Bioinformatics

Database for Simple Sequence Repeats of Takifugu rubripus

Bioinformatics

Database of Diterpene Synthase Gene

Bioinformatics

Database of Flora of Indian Desert  

Bioinformatics/ Plant Science

Database of Plant Host-Pathogen Interaction

Bioinformatics/ Plant Science

Manpower Training:
To generate trained manpower in Bioinformatics, National Workshops with participation of University level teaching faculty/ Scientists are regularly organized by the Centre. The following workshops were organized in past:  

      Table:
      The following workshops were organized by the Centre for Bioinformatics, Dept. of Bioscience & Biotechnology during
      the last few years:  
  

“Application of Internet in Advanced Teaching and Research in Biological Sciences”

3 days

“Application of Information Technology in Biotechnology based research”

“Trends in Bioinformatics”

“Bioinformatics Basics- Application in Biological Sciences”

“Biological Databases and Data  Mining” 

"Biological Databases and Data Mining Approaches "

List of Publications:

Bioinformatics research papers published in peer reviewed journal by our centre:

1. Gautam, B., Katara, P., Singh, S. and Farmer, R. 2010. Drug target identification using gene expression microarray data of Toxoplasma gondii. International J. Biometric & Bioinformatics, 4(3): 113-124.
2. Katara, P., Sharma, N., Sharma, S., Khatri, I., Kaushik, A., Kaushal, L. and Sharma, V. 2010. Comparative microarray data analysis for the expression of genes in the pathway of glioma. Bioinformation, 5(1): 31-34.
3. Katara, P., Singh, A., Raghav, D. and Sharma, V. 2010. Analysis of regulatory genomics and gene expression pattern of medicinal importance genes of Helicobacter pylori. J. Computer Science and Systems Biology, 3(1): 010-015.
4. Katara, P., Grover, A., Kuntal, H. and Sharma, V. 2010. In silico prediction of drug targets in Vibrio cholerae. Protoplasma (In Press).
5. Katara, P., Sanghi, N. and Sharma, V. 2010. In Silico analysis of regulatory elements of antibiotic producing genes in Streptomyces species. International J. Pharmaceutical Sci. Review and Res., 4: 099-103.
6. Katara, P., Gautam, B., Kuntal, H. and Sharma, V. 2010. Prediction of miRNA targets affected proteins and their homologs in Glycine max. Bioinformation, 5(4): 162-165.
7. Katara, P., Agarwal, M., Jeena, G., Karkra, S., Sharma, I. and Sharma, V. 2009. In- silico prediction of the regulatory element patterns of human pathogen Mycobacterium tuberculosis. Int. J Biotechnology and Biochemistry 5(1): 7-13.
8. Singh, A., Katara, P. and Sharma, V. 2009. Drug Discovery Process: An Overview. Biobytes, 4: 40-43.
9. Shanker, A. and Sharma, V. 2009. Annotation Jargon- It’s not too late to correct it. Current Science, 97: 983-984.
10. Shanker, A., Sharma, V. and Daniell, H. 2009. A novel index to identify unbiased conservation between proteomes. IJIB, 7: 32-38.
11. Singh, A., Mishra, S., Raghav, D., Shanker, A. and Sharma, V. 2008. In-silico method for the identification of Mycobacterial sp. Potential drug targets. ICCES, 174: 1-5.
12. Katara, P. and Sharma, V. 2008. In-silico prediction of the essentiality of osmoprotectant genes of Pseudomonas aeruginosa. J. Computational Intelligence in Bioinformatics, 1(2-3): 143-148.
13. Shanker, A., Bhargava, A., Bajpai, R., Singh, S., Srivastava, S. and Sharma, V. (2007). Bioinformatically mined simple sequence repeats in unigene of Citrus sinensis. Sci. Horti. 113: 353-361.
14. Shanker, A., Kumar, A., Sangwan, C., Chowdhary, N., Gupta, S., Sonica and Sharma, V. 2007. Orthologous and essential genes identification in Cryptococcus neoformans and Neurospora crassa. In joint Indo Korean Symposium on Biochemical Engineering & Biotechnology, 22nd -24th February, New Delhi, India.
15. Shanker, A., Tripathi, D., Khandelwal, G., Sharma, G., Agrawal, S., Singh, A. and Sharma, V. 2006. Data mining and database development for simple sequence repeats of Takifugu rubripes (Japanese Pufferfish). Biochem. Cell. Arch., 6: 1-12.
16. Shanker, A., Singh, A. and Sharma, V. 2006. In silico mining in expressed sequences of Neurospora crassa for identification and abundance of microsatellites. Microbiological Research, 162: 250-256.